A Rare Case of Central Diabetes insipidus in Pregnancy

Potharlanka P B Eswari; Gudivaka dasarathi; Swarna Latha G

Volume : VI, Issue : V, May - 2016

A Rare Case of Central Diabetes insipidus in Pregnancy

Potharlanka P B Eswari, Gudivaka Dasarathi, Swarna Latha G

Abstract :

A 30yr old primi at 29wks of gestational age was referred to us with altered sensorium since one day & past history of polyuria, polydipsia since childhood. She had no focal neurological signs, hemodynamically stable with sodium 191 meq/L, potassium 4.4meq/L, Urine, serum osmolality 44 and 390 mOsm/L, respectively. Her urine output in hospital was 4.5 to 12.5 lit/day. She responded well with desmopressin and delivered a 1.55kg female child by LSCS at 32wks due to severe oligohydramnios. MRI ain showed absent ight spot. Diabetes insipidus is rare in pregnancy though pregnancy itself can worsen the condition. Diabetes Insipidus is either due to arginine vasopressin deficiency (central) or due to tubular unresponsiveness (nephrogenic). Our patient is a case of central diabetes insipidus whose symptoms are improved well with desmopressin therapy