Volume : VIII, Issue : III, March - 2018

A RARE CASE OF MARCHIAFAVA BIGNAMI SYNDROME IN A CHRONIC ETHANOLIC PATIENT

Dr Prathap Bingi, Dr Brungi Mahesh

Abstract :

 

Marchiafava–Bignami disease (MBD) is a rare condition characterized by demyelination and degeneration of the corpus callosum seen in patients with chronic alcohol intake. This may also rarely occur in non alcoholics who are chronically malnourished. The etiopathogenesis of this condition is based on a complex deficiency of group B vitamins especially in alcoholics. Many patients improve with supplementation of these vitamins. However, a good response is not always observed. The definitive diagnosis of Marchiafava–Bignami disease can be problematic and is based on features of neuroimaging studies, especially magnetic resonance imaging. The present article is a case report of a Marchiafava–Bignami disease in an alcohol–dependent male patient who improved after the administration of parenteral B vitamins. This article also gives a review of literature of Marchiafava Bignami disease.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr Prathap Bingi, Dr Brungi Mahesh, A RARE CASE OF MARCHIAFAVA BIGNAMI SYNDROME IN A CHRONIC ETHANOLIC PATIENT, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-3 | March-2018

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