A RARE CASE REPORT– CASTLEMAN‘S DISEASE IN LYMPH NODE IN 41 YEAR MALE

Dr. Mahendra Singh; Dr. Anita Omhare; Dr. Somya Goyal; Dr. Vandana Mishra; Dr. Swaraj Kumar Sharma

Volume : VIII, Issue : I, January - 2018

A RARE CASE REPORT– CASTLEMAN‘S DISEASE IN LYMPH NODE IN 41 YEAR MALE

Dr. Mahendra Singh, Dr. Anita Omhare, Dr. Somya Goyal, Dr. Vandana Mishra, Dr. Swaraj Kumar Sharma

Abstract :

Castleman disease, also known as angiofollicular lymph node hyperplasia is a group of uncommon lymphoproliferative disorders that share common lymph node histological features. It was first described by Dr. Benjamin Castleman in the 1950s. Castleman‘s disease has two main forms: localized to a single lymph node (unicentric) or occur systemically (multicentric). Even though CD is not officially a cancer, one form of this disease (known as multicentric Castleman disease) acts very much like lymphoma. In fact, many people with this disease eventually develop lymphomas. And like lymphoma, CD is often treated with chemotherapy or radiation therapy. We present a case of 41 year old male who presented with right inguinal lymphadenopathy which was excised and sent for histopathology. On histopathological examination, lymphoid follicles show hyalinised blood vessels and prominent interfollicular stroma with large number of plasma cells and fair number of Russell bodies. Thus, diagnosis of Castleman disease was made.