A Retrospective Haematological Study of Myeloproliferative Neoplasms in a Tertiary Care Centre

Bidhan Ch. Das; Vishal Agarwal

Volume : VII, Issue : VI, June - 2017

A Retrospective Haematological Study of Myeloproliferative Neoplasms in a Tertiary Care Centre

Bidhan Ch. Das, Vishal Agarwal

Abstract :

Myeloproliferative neoplasms (MPN) are a group of stem cell disorders characterised by overproduction of mature white cells, red cells or platelets suggesting that the maturation of the neoplastic cell line is relatively normal. The present study was conducted to have haematological interpretation in the diagnosis of myeloproliferative neoplasms. This study was performed over a peroid of 1 year from May 2016 to April 2017. The complete haemograms were done and slides were prepared with peripheral blood and in selected cases bone marrow aspirates which were stained by leishman stain. Cytogenetic study was done in majority of cases to confirm the diagnosis. In our study, 42 cases of myeloproliferative neoplasms were reported. After confirmation, 41 cases (97.62%) were reported as chronic myeloid leukemia (CML) and the rest 1 case (2.38%) was considered as chronic neutrophilic leukemia (CNL). This study concluded that CML is the most common myeloproliferative neoplasm. Males are more commonly affected than females. The cytogenetic study is mandatory for confirmation of MPN.