A Study of Association between Serum Magnesium level and Acute Exacerbation of COPD Patients at a Tertiary Care Hospital.

Dr.Viney Sambyal; Dr.Shabaz Khan

Volume : IX, Issue : II, February - 2019

A Study of Association between Serum Magnesium level and Acute Exacerbation of COPD Patients at a Tertiary Care Hospital.

Dr. Viney Sambyal, Dr. Shabaz Khan

Abstract :

Background: The course of COPD is associated with exacerbations. There are many factors responsible for exacerbations. A decrease in serum Mg+2 is associated with airway hyper–reactivity and impaired pulmonary function. The purpose of this study was to determine if decreased serum Mg+2 levels in patients with chronic obstructive pulmonary disease (COPD) are associated with acute exacerbations. Aims and Objectives: To study the association of serum Magnesium level with acute exacerbation and also to know the relationship between Serum Magnesium levels and frequency of exacerbations. Materials and Methods: The study was conducted among 286 COPD patients admitted in Govt. Medical College and hospital Jammu from January 2018 to December 2018. A detailed history was elicited, clinical examination and all required investigations were done in all cases. Patients with age above 40 years only included and patients associated with other conditions producing hypo or hypermagnesemia were excluded from this study. Statistical methods:The data was analysed with the help of software such as SPSS16, Microsoft Excel 2018. Results: Magnesium was at low level in patients who presented with acute exacerbation, normal in stable COPD patients (P value – 0.002). And number of admissions also more in COPD patients with exacerbations. Conclusion: Hypomagnesemia is seen in COPD patients with exacerbations. And also there was more frequent exacerbations found in patients with Hypomagnesemia. So Magnesium is one of the independent and modifiable risk factor for COPD exacerbation