A STUDY OF CARDIAC MANIFESTATIONS IN OVERT AND SUBCLINICAL HYPOTHYROIDISM

Dr. P. Lalitha; Dr. P. Sruthi Sipra; Dr. B. Sarat Chandra

Volume : X, Issue : I, January - 2020

A STUDY OF CARDIAC MANIFESTATIONS IN OVERT AND SUBCLINICAL HYPOTHYROIDISM

Dr. P. Lalitha, Dr. P. Sruthi Sipra, Dr. B. Sarat Chandra

Abstract :

BACKGROUND: Thyroid hormones are very important for the normal functioning of the heart. This study aims at studying the cardiovascular consequences in hypothyroid patients by electrocardiography, lipid profile, and echocardiography. METHODS: This is a cross–sectional study conducted on 100 cases of hypothyroidism with a structured questionnaire to collect information from subjects regarding history, clinical examination, and investigations. ECG, 2D ECHO, and lipid profile were done to find the cardiac changes and diastolic dysfunction. RESULTS: Out of the 100 cases, 82 had overt hypothyroidism, and 18 had subclinical hypothyroidism. Females constituted 80%, and the majority of them were in the age group > 50 years (34%). Commonest symptom on presentation was Dyspnea (65%). Dyslipidemia is seen in 34 patients. On ECG, 38% had Bradycardia, 24% had abnormal LVC, 9% had ST–T changes, 10% had long QT, 4% had RBBB. On Echo, 21% had pericardial effusion, 5% had LV Hypokinesia, and among subjects with Overt Hypothyroidism, 45% had diastolic dysfunction and 10% among those with Sub Clinical Hypothyroidism. CONCLUSION: The study concludes that there is a significant association of hypothyroidism with diastolic dysfunction and pericardial effusion, particularly in the overt hypothyroidism group