Volume : VII, Issue : V, May - 2017

A STUDY OF CLINICAL PROFILE OF TUBERCULOSIS IN PRE AND POST RENAL TRANSPLANT PATIENTS

Dr. R. Arul, Dr. P. Arun Prasath, Dr. Jegan, Dr. P. Praveen Kumar

Abstract :

 Tuberculosis is one of the most common bacterial infections in developing countries. Uremia is an acquired immunodeficiency state with functional abnormalities of neutrophils and T and B lymphocytes, monocytes and natural killer cells. Risk of infection in post renal transplant recipients is primarily determined by immunosuppression and immune status.  We compared the demographic characteristics, clinical and  laboratory variables between pre renal transplant (chronic  kidney disease and dialysis patients) and post renal transplant patients. Total of 47 patients were included in the study. Out of 47 patients, 21 patients were CKD without dialysis and 12 patients were on dialysis and 14 patients were post renal transplant recipients. Pulmonary TB was seen in 43%(20) patients. Pleural TB was seen in 24%(11).  X ray features of consolidation was found in 45%(9/20) and cavitation presents in 15%(3/20) of patients. Lower lobe involvement is present in 20% (4/20) of patients.  Sputum AFB positivity was seen in 26% (6/20) of patients with pulmonary involvement. Past history of TB was present in (6/47)12% of patients. In CKD patients without dialysis, 38%(8) are CKD  stage3 and 38%(8) are CKD  stage 4 and 24% (5) patients are CKD stage 5 without dialysis. In post–transplant recipients 50 %(7) had pulmonary TB. 22%(3) patients had pleural TB.  

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. R.ARUL, Dr.P.ARUN PRASATH, Dr.JEGAN, Dr.P.PRAVEEN KUMAR, A STUDY OF CLINICAL PROFILE OF TUBERCULOSIS IN PRE AND POST RENAL TRANSPLANT PATIENTS, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾5 | May‾2017

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