Volume : VII, Issue : VIII, August - 2017
A STUDY OF EXERCISE TREADMILL TEST IN DETECTING ASYMPTOMATIC CORONARY ARTERY DISEASE IN TYPE 2 DIABETES MELLITUS
Paul Joy Pazhampillil, Sundaraj Ravindran, Prasannan Gokul
Abstract :
INTRODUCTION: Patients with type2 DM show a greater risk for CAD. But the risk stratification in asymptomatic CAD patients has not been established. This study investigated the prevalence of CAD in type2 DM patients since CAD accounts for 70–80 % of mortalities in diabetic patients. CAD risk for those with type2 DM is as great as that associated with a previous history of MI. However progressive CAD is asymptomatic in many cases of type 2 DM ,which is difficult to diagnose at proper time.The diagnosis of
asymptomatic CAD in type 2 diabetic patients is largely made based on the recommendations of ADA.The ADA recommends tat DM patients perform a treadmill exercise test(TMT) if they have additional cardio vascular risk factors.how ever clinically significant severe CAD is often discovered in patients with fewer risk factors
AIMS AND OBJECTIVES:
1. To assess the prevalence of coronary artery disease in type 2 diabetes
without hyper tension with normal ECG &normal echo
2. To improve the long term survival of type 2 diabetic patients by
early detection of coronary artery disease and timely institution of
Treatment
MATERIALS&METHODS:
The study was conducted among out patients
from diabetology & cardiology departments of Government Rajaji Hospital,
Madurai during the period of January 2016 to June 2016. The study included
100 diabetic patients who had no previous symptoms of any cardiac disease.
Subjects believed to fulfill all eligibility criteria, and none of the exclusion
criteria were included in the study.
METHODOLOGY:
A previously designed proforma is used to collect the
demographic data ,history and clinical details of the patients.
A battery of diabetic profile tests are done in all cases to assess glycemic
status . 12 lead ECG is taken to all patients .Those who are showing normal
results are subjected to ECHO. If they show normal observation they will be
subjected to exercise induced treadmill test in all patients for half an hour. Any
exercise induced ischemia, MI, LBBB, any arrhythmias, are observed from the
ECG which is recorded. Comparisons of inducible ischemia in blood sugar
levels of fasting, Hba1c, BMI, ppbs are observed. Significance assessed by
Students t test. Relation between age, sex, and duration of diabetes are assessed
by Pearson correlation test.
STATISTICAL ANALYSIS:
STUDENTS T TEST, PEARSON CORRELATION TEST, ONE WAY ANOVA ,CHI SQUARE TEST
RESULTS:
The average age for study group was 54.92 years. Among the 100
patients studied 60 were males and 40 females . Among the cases studied 40
had inducible ischemia .Of these 40, 23 having 5–10 years duration of diabetes
,9 cases having more than 10 years of diabetes. Rate of inducible ischemia was
high in patients with high fasting, high BMI, high HbA1C compared to
patients with good glycaemic controls patients .Among the cases rate of
occurrence of ischemia was higher in those with poor glycaemic control than
with good glycemic control .Occurrence of ischemia significantly high in
patients even they are not having any symptoms of cardiac diseases. Based on
TMT results we can observe that CAD risk is high even at the age of 40 and rate
of ischemia occurrence is high if good glycemic control is not maintained.
CONCLUSION:
Type 2 diabetic patients are more prone for CAD since it is a coronary equalent.
Hence all diabetics after the age of 40 should be subjected to TMT as a
screening tool to diagnose early CAD .
Keywords :
Article:
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DOI : 10.36106/ijar
Cite This Article:
Paul Joy Pazhampillil, Sundaraj Ravindran, Prasannan Gokul, A STUDY OF EXERCISE TREADMILL TEST IN DETECTING ASYMPTOMATIC CORONARY ARTERY DISEASE IN TYPE 2 DIABETES MELLITUS, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾8 | August‾2017
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Paul Joy Pazhampillil, Sundaraj Ravindran, Prasannan Gokul, A STUDY OF EXERCISE TREADMILL TEST IN DETECTING ASYMPTOMATIC CORONARY ARTERY DISEASE IN TYPE 2 DIABETES MELLITUS, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾8 | August‾2017
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