Volume : VII, Issue : V, May - 2017

A STUDY OF LIPID PROFILE IN DIABETES MELLITUS

Dr. Venkateshwarlu Rajuri

Abstract :

 BACKGROUND:               Diabetes is the most common non–communicable disease globally.             . It is estimated that nearly 380 million adults worldwide will have diabetes by 2025.India has 41 million diabetics and this number is expected to increase to 70 million by 2025.             Diabetes is characterized by chronic hyperglycemia and disturbances of carbohydrate, lipid and protein metabolism. We aimed to research association between serum lipid profile and blood glucose, hypothesizing that early detection and treatment of lipid abnormalities can minimize the risk for atherogenic cardiovascular disorder and cereovascular accident in patients with type 2 diabetes mellitus. AIM & OBJECTIVES: 1. To determine the association between lipid profile with type 2 Diabetes mellitus in relation to age, sex and duration of diabetes. 2. To study the occurrences of vascular complications in type 2 Diabetes mellitus. STUDY DESIGN: Cross sectional observational study. MATERIALS AND METHODS:          The present  study was undertaken  between  the years  2013–2015 at CAIMS  (Chadalawada Anandarao Institute of Medical Sciences).Total sample size 100 of which the study group consists of  Fifty type–2 diabetic  patients  and not on Lipid lowering  agent.        The remaining fifty formed healthy control group. Their cholesterol levels and vascular complications were measured and compared. RESULTS:                                                                     Results indicate a significance increase in serum VLDL – C, TG and LDL   along   with   a   significant decrease   in serum   HDL–C   among diabetics as compared to non diabetics.            Total cholesterol, TG and LDL was increased  among  34%,  64% and  60% of the study group when cutoff values were taken as TC > 200 mg/dl, TG > 150  rng/dl  and LDL> 100 mg/dl.  HDL was reduced among 72% of the study subjects when HDL < 40 mg/dl was taken as cutoff values. CONCLUSIONS:    The  alteration  of  lipid  metabolism  of type–2  diabetics  has  raised  a serious  medical  concern  with  respect to vascular  complications  like coronary artery disease, cerea vascular diseases and the recommendation of greater routine evaluation  of serum lipid  profile and its  treatment  among  both  treatment naïve and treatment initiated  type–2 diabetes mellitus strongly suggested

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. VENKATESHWARLU RAJURI, A STUDY OF LIPID PROFILE IN DIABETES MELLITUS, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾5 | May‾2017

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