A STUDY OF RIFAMPICIN RESISTANCE AMONG TUBERCULOSIS CASES ATTENDING RNTCP CENTER GGH, VIJAYAWADA.

Dr.R.Lakshmi Kumari; Dr.Nirupama P Bondili; Dr.K.Parameswari

Volume : VII, Issue : II, February - 2017

A STUDY OF RIFAMPICIN RESISTANCE AMONG TUBERCULOSIS CASES ATTENDING RNTCP CENTER GGH, VIJAYAWADA.

Dr. R. Lakshmi Kumari, Dr. Nirupama P Bondili, Dr. K. Parameswari

Abstract :

Aims and objectives: To study the Rifampicin resistance among CBNAAT diagnosed cases of Tuberculosis and to compare the data of HIV reactive cases with their CD₄ counts.

Materials and Methods: This is a prospective study conducted at GGH, Vijayawada. 2347 samples from suspected TB cases were submitted for CBNAAT (Xpert MTB/RIF assay). The data was analysed in relation to CD4 counts among PLHIV & Extra pulmonary cases, suspected paediatric TB & smear negative cases.

SUMMARY: Among the 2347 tested patients 269 were positive for TB. Out of 269 positives 235(87.36%) are HIV reactive & 34(12.63%) are HIV non reactive. Rifampicin resistance is 3.40 %(8) among HIV reactive & 32.35%(11) among HIV non reactive cases. An attempt is made to correlate these results with CD4 counts in HIV reactive patients.