A STUDY OF ROLE OF CO–MORBID DEPRESSION ON NEUROPSYCHOLOGICAL DEFICITS IN OBSESSIVE–COMPULSIVE DISORDER

Mithlesh Khinchi; Sanjay Jain; Rajesh Sharma

Volume : VIII, Issue : VI, June - 2018

A STUDY OF ROLE OF CO–MORBID DEPRESSION ON NEUROPSYCHOLOGICAL DEFICITS IN OBSESSIVE–COMPULSIVE DISORDER

Mithlesh Khinchi, Sanjay Jain, Rajesh Sharma

Abstract :

Introduction– Depression is commonly comorbid with OCD and There has been considerable interest in the neuro–cognitive functioning of subjects with depression, OCD and also depression with OCD since long time. The cognitive dysfunctions that have been demonstrated in the patients of OCD could in part be because of co–morbid depression.

Aim: To assess neuropsychological deficits in patients suffering from OCD & co–morbid depression, to compare the magnitude of neuropsychological deficits in OCD patients in relation to severity of co–morbid Depression

Methodology—it’s a cross sectional study and included 72 patients of OCD having score < 20 on BDI scale with depression and OCD having score ≥20 on BDI scale who attending OPD at psychiatric Centre, Jaipur and Control group had 36 healthy persons matched for age and education. To enter in the study, patient was screened with a specially designed screening Performa, which encompassed the entire exclusion criteria, followed by application of various neuropsychological tests applied.

Results– We found that patients with OCD with moderate/severe depression showed higher neurocognitive impairment in domains of attention and working memory, verbal learning and delayed recall, visuso spatial recognition and memory, executive functioning, visuoconstructual and visuo motor speed, shifting attention, perseverance, when compare to OCD with mild Depression.

Conclusion– Cognitive impairment was presents both in moderate/severe depressed as well as mild depressed OCD patients. ButOCD with moderate/severe depression showed greater cognitive impairment than OCD with mild depression.