A study of safety profile of renal biopsy procedure in children with Nephrotic syndrome

Dr Trupti Joshi; Dr Amol Joshi; Dr Sonal Shah

Volume : VI, Issue : VIII, August - 2016

A study of safety profile of renal biopsy procedure in children with Nephrotic syndrome

Dr Trupti Joshi, Dr Amol Joshi, Dr Sonal Shah

Abstract :

Introduction: Percutaneous renal biopsy (PRB) of native kidneys has become an essential tool in the management of patients with renal disease. Renal biopsy can be used as a diagnostic tool in view of multifactorial etiology and variable structural derangements in Nephrotic syndrome. Since the introduction of PRB in the 1950s, technical advances in imaging and biopsy needles have simplified and improved the success of the procedure with minimal complications. Aims and Objectives: Study of safety profile of renal biopsy procedure in children with Nephrotic syndrome. Methodology: This was a cross–sectional study of children with Nephrotic syndrome, who underwent PRB procedure at a tertiary health care center during one year period. Total 22 pediatric patients of Nephrotic syndrome with indication of renal biopsy were included in the study. Ultra Sound guided PRB procedure was performed with a biopsy gun (Bard Max Core Disposable Instrument) and complications of the procedure were observed for 24 hours in these children and repeat Ultrasound was done at discharge. Result: Most common indication for renal biopsy in this study group was “Atypical (<1yr & > 8yrs) age of diagnosis in 10/22 (45.5%) patients, followed by (5/22 (22.7%) children presenting with hypertension & hematuria. Only 2/22 (9%) patients who underwent PRB procedure had complications. One of them had gross hematuria and the other one had perirenal hematoma, both resolved spontaneously. Conclusion: Ultrsound guided PRB procedure is reasonably a safe procedure in children with Nephrotic syndrome.