Volume : X, Issue : II, February - 2020

A STUDY OF SERUM MAGNESIUM LEVELS IN CEREBROVASCULAR ACCIDENTS

Dr. A Swetha Rani, Dr. Namburu Sindhura, Dr. G. Vijaya Kumar

Abstract :

Background : Cereal Stroke is a major cause of mortality worldwide and commonly occurs among elderly. It is third major cause of death in developed countries after cardiovascular disease and cancer. Magnesium is 4th most abundant cation in the body and its deficiency triggers vasoconstriction, enhances vascular endothelial injury and leads to atherosclerosis. Prophylactic use of magnesium can inhibit the disability in patients due to ischemic stroke in future and can reduce social, emotional and economical loses among them. Aim : To study the association of serum magnesium levels in patients with cereovascular accidents. Materials and Methods: A Hospital based Prospective study was conducted in Department of Medicine, Santhiram medical college & general hospital for a 1 year period. Total 100 subjects, 50 cases of cereovascular accidents and 50 age and sex matched controls without CVA‘s attending the medicine department satisfying the inclusion criteria were included for the study. Diagnosis of stroke was confirmed by CT ain or MRI. Then approximately 2ml of venous sample was collected from subjects and Serum magnesium levels were estimated by CALMAGITE method, and results were compared between cases and controls. Results: In our study, 50 controls and 50 cases were taken. Out of 50 cases, 36 were ischemic(72%), 10 were hemorrhagic(20%) and 4 were TIA(8%). Out of 50 cases, 34 were males(68%) and 16 were females(32%). More number of cases were in the age group of 61–70 years(38%). Mortality has been observed in the age group of 80 to 90 years(85%) with their mean serum magnesium level less than 1.0mg%(85%). Mortality is more observed in males (71.5%), than females(28.5%). Mean serum magnesium level of control and cases were calculated, and p–value was extremely significant (<0.0001). Conclusion: There was significant low serum magnesium level noted in the patients who presented to emergency department with stroke. Mortality has been observed in the age group of 80 to 90 years (85%) with their mean serum magnesium level less than 1.0 mg% (85%). Mean Serum magnesium level of control and cases were calculated, and p value was extremely significant (<.0001). Hence cereovascular accidents are more commonly associated in patients with low serum magnesium levels

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

A STUDY OF SERUM MAGNESIUM LEVELS IN CEREBROVASCULAR ACCIDENTS, Dr. A Swetha Rani, Dr. Namburu Sindhura, Dr.G. Vijaya kumar INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-2 | February-2020

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