A Study of the Determination of Corneal Endothelial Cell Count in Patients with Primary Glaucoma

Anjana Mirajkar; Shubha Napal; Sanjeev Agrawal

Volume : IX, Issue : V, May - 2019

A Study of the Determination of Corneal Endothelial Cell Count in Patients with Primary Glaucoma

Anjana Mirajkar, Shubha Napal, Sanjeev Agrawal

Abstract :

Introduction: Present study aimed to determine the corneal endothelial cell count in adult patients with primary glaucoma (POAG, PACG and NTG) and to compare the corneal endothelial cell count in age matched normal individuals. Materials & Methods: The study was conducted at the Ophthalmology Department of Bharati Hospital, Pune. A total of 194 eyes of patients having primary glaucomas (POAG, PACG, NTG) between age group of 20 to 80 were included in this study along with 196 eyes of age matched controls (with no ocular complaints or systemic ailments). The endothelial cell count in both the groups was measured with the help of specular microscope. Data was analysed by SPSS ver. 21.0. Results: The average endothelial cell count in the POAG was 2661.342 cells/mm2 and in PACG was 2280.22 cells/mm2 and in NTG was 2614.67 cells/mm2 and in the control group was 2781.21 cells/mm2. There was significant (p<0.05) endothelial cell loss in POAG and PACG in age groups of 40 to 80 years of age but the cell loss was not significant in NTG group in 40 to 60 age group (p<0.05). There was no significant cell loss in age group of 20 to 40 years in all glaucoma types. Conclusion: Endothelial cell counts were significantly lower in patients with POAG and PACG when compared with controls. Thus evaluation of corneal endothelium is necessary before proceeding to intraocular procedures in glaucoma patients.