A Study on Clinical Profile and Outcome of Acute Encephalitis Syndrome (AES) patients in a Tertiary Care Centre in Eastern Bihar.

Dr Shashi kant; Dr Brajesh Kumar

Volume : X, Issue : VI, June - 2020

A Study on Clinical Profile and Outcome of Acute Encephalitis Syndrome (AES) patients in a Tertiary Care Centre in Eastern Bihar.

Dr Shashi Kant, Dr Brajesh Kumar

Abstract :

Aims and Objective: Acute encephalitis syndrome (AES) is a serious public health problem, caused mainly by viruses. Acute encephalitis syndrome is a cause of significant morbidity and mortality in Eastern Bihar. Although Japanese encephalitis virus (JEV) was thought to be a major cause for acute encephalitis syndrome, more non–Japanese encephalitis virus cases are reported. The outcome of patients with acute encephalitis syndrome is variable. Our study was designed to study the clinical profile and outcome of patients with acute encephalitis syndrome managed in tertiary care center in Eastern Bihar. Methods: In the present study, record of patients admitted with diagnosis of acute encephalitis syndrome, from May 2019 to April 2020 in Jawahar Lal Nehru Medical College and Hospital, Bhagalpur, Bihar was reviewed. They were classified clinically as meningitis, encephalitis and meningoencephalitis. The clinical details and reports of the patients were recorded and analyzed accordingly. Results: In this study, total 85 cases of meningitis and encephalitis were identified. Fifty–six (65.9%) patients were males and 29 (34.1%) were females. Sixty (70.58%) patients had meningitis, 8 (9.41%) had encephalitis, and 17 (20.0%) had meningoencephalitis. JE serology was positive in 4 patients (4.7%). Seventy–two (84.7%) patients made full recovery and were discharged from hospital. Thirteen (15.3%) patients left against medical advice (LAMA) without getting full treatment at the hospital. Conclusion: Acute encephalitis syndrome is still a major public health problem in Eastern Bihar especially childrens. Few of these patients have Japanese Encephalitis. There is a trend towards improved outcome because of availability of improved health services. Financial constraint remains a major challenge in management of AES in resource poor country like India. So adequate measures needs to be taken to prevent our children from morbidity and mortality of this deadly disease