A STUDY ON OCULAR MANIFESTATIONS OF TUBERCULOSIS AND PROGNOSTIC VALUE OF ANTI-TUBERCULAR TREATMENT

Dr. Priyanka Gupta; Dr. Swati Kujur; Dr. M. L. Garg

Volume : VIII, Issue : III, March - 2018

A STUDY ON OCULAR MANIFESTATIONS OF TUBERCULOSIS AND PROGNOSTIC VALUE OF ANTI-TUBERCULAR TREATMENT

Dr. Priyanka Gupta, Dr. Swati Kujur, Dr. M. L. Garg

Abstract :

MATERIAL AND METHODS :– A Interventional Prospective study was conducted at Upgraded Department of Ophthalmology, Pt. J.N.M. Medical Collage and Dr. B .R. A. M. Hospital,Raipur from January 2016 – June 2017. Patients having diagnosed or suspected case of ocular tuberculosis or systemic tuberculosis with ocular complaints attending OPD or admitted in ward of department of Ophthalmology, Dr.B.R.A.M.Hospital, Raipur Chhattisgarh (C.G.) were recruited. History , clinical & ophthalmological examination e.g.–Visual acuity determination, torch light examination, Slit lamp examination, Fundus examination done. Investigations–Hematological, Biochemical, Chest X–Ray(PA–view), B–Scan, Mantoux test, Sputum for AFB, HIV, HbS–Ag test, some special test like TB–Gold , CB–NAAT test done.

RESULTS & DISCUSSION :–40 patients were recruited having systemic tuberculosis with ocular manifestation or diagnosed or suspected case of ocular tuberculosis with male:female ratio–1.6:1(25:15). Tuberculosis can affect any part of eye.We have got different ocular manifestations of tuberculosis– e.g.–Anterior staphyloma with granuloma, Ptosis, Scleritis, Conjunctival dryness, Conjuntivitis, Corneal ulcer, Complicated cataract, Uveitis(anterior, posterior & pan–uveitis), Retinal detachment, Optic atrophy & pale disc. Significant number of patients were mantoux test positive (39 out of 40). AFB sputum was negative in all patients. Chest X–ray suggestive of tubercular changes found in very few patients. Significant number of patients shows visual or structural improvement after starting of anti–tubercular treatment. Few patients also receive systemic steroid to decrease intraocular inflammation.

CONCLUSION :– Significant proportion of patients show ocular manifestation of tuberculosis . Most common ocular manifestation is uveitis. Significant number of patients showed improvement after starting of anti–tubercular treatment.