A Study to Diagnose Prostatic Neoplasm on the Basis of Trans–Rectal Ultrasound–Guided Prostatic Biopsy

Dr Manish Bhagat; Dr Deepak Varshney; Dr Rupali Gupta; Dr Santeshwari

Volume : VII, Issue : VIII, August - 2017

A Study to Diagnose Prostatic Neoplasm on the Basis of Trans–Rectal Ultrasound–Guided Prostatic Biopsy

Dr Manish Bhagat, Dr Deepak Varshney, Dr Rupali Gupta, Dr Santeshwari

Abstract :

Background: Presently gold standard to differentiate and diagnose the prostatic non–neoplasm and neoplasm, is a Transrectal ultrasound (TRUS) guided biopsy of the prostate.

Objectives To differentiate and diagnose the different types of prostatic diseases – non–neoplastic {benign prostatic hyperplasia (BPH), prostatitis and prostatic abscess} and neoplastic diseases by TRUS–guided biopsy of the prostate in patients with increased serum prostatic specific antigen (PSA) levels with or without symptoms of Prostatomegaly.

Patients and methods

This is a prospective study carried out on all patients (60 patients ) having symptoms suggestive of prostatic diseases with increased serum PSA, presented in the Department of Radiology, SAIMS, Indore from March 2016 to Feb 2017. All these patients were subjected to DRE, serum prostate–specific antigen testing in their referring department. These patients underwent TRUS–guided prostate biopsies to diagnose the prostatic diseases. Increased serum PSA level randomly was divided into mild (≥ 4 to 10ng/ml), moderate (≥ 10.1 to 20 ng/ml) and marked elevations (20.1 ng/ml & more). In most cases, twelve cores tissue were taken and sent in 12 separate formalin bottles. These bottles were sent to the pathology department.

Result: In our study, the mean age of all patients was 66.47± 8.88years; (range from 48 to 85 years). On the basis of our study, there is no significant difference in an age in these two group.

The mean serum PSA value was 31.49± 23.70 ng/ml. The mean PSA was significantly higher in the cancer group than in the benign group. Out of total 60 cases, 36(60%) cases were having neoplastic lesions, however, the remaining 24 (40%) showed non–neoplastic lesions.

Conclusions The detection rate of prostate cancer is similar to that reported previously from around the world and rises with an increase in serum PSA level.