Volume : VIII, Issue : XII, December - 2018

A STUDY TO EVALUATE CRP AS A PROGNOSTIC MARKER IN ACUTE ISCHAEMIC STROKE

G. Yashwanath Reddy, Nishanth T

Abstract :

 INTRODUCTION: Stroke remains a major cause of human mortality and morbidity. In spite of our increasing understanding of the pathophysiology and epidemiology of cardiovascular diseases and stroke and continuing advances in prevention and treatment, the burden of above said diseases is high. AIMS OF THE STUDY: To observe plasma CRP levels in acute ischemic stroke. To evaluate the role of CRP(C–Reactive protein) as a prognostic and diagnostic aid in acute ischaemic stroke. To evaluate CRP levels as a risk factor in acute ischemic stroke. METHODOLOG: The present study was a hospital based, prospective, case control study conducted on 60 patients and 60 age and sex matched controls admitted with clinically first attack of stroke to medicine intensive care unit or acute medical ward of SVS medical college & Hospital, Mahabubnagar between september 2015 to august 2017. RESULTS: Of the total 60 patients 37 were males and 23 were females with male to female ratio of 1.6:1. The maximum thrombotic stroke patients were in the age group of 61 – 70 constituting 30% of the study population. 82% of patients had sudden onset of symptoms while 11% developed the symptoms gradually. (33.3%) had infarction in the parietal lobe, followed by frontal and fronto–parietal areas which had 13.4% each. Diabetes was the most important risk factor for acute ischaemic stroke affecting 33.4% of the cases. Smoking was the most common non–modifiable risk factor(26.6%).There was statistically significant  rise in systolic and diastolic blood pressure in case compared to controls. Elevation of CRP and lipid profile parameters in patients were statistically significant compared to controls. CONCLUSION: Stroke incidence increases with advancing age and is more in males when compared to females. C–reactive protein is an independent risk predictor for ischemic stroke. C–reactive protein level increases as age advances and has no significant gender predilection. C–Reactive level cannot differentiate the subtypes (cortical and sub cortical) of cereal infarct at the time of early diagnosis. C–Reactive protein is a sensitive parameter to predict future stroke

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

A STUDY TO EVALUATE CRP AS A PROGNOSTIC MARKER IN ACUTE ISCHAEMIC STROKE , G.Yashwanath Reddy, Nishanth T , INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8|Issue-12| December-2018

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