A STUDY TO EVALUATE HISTOPATHOLOGICAL VARIATIONS IN ENDOMTERIAL BIOPSIES IN A TERTIARY CARE HOSPITAL

Mrs A.R.Jaswanthini; Ms Ruchita D Jain

Volume : IX, Issue : XII, December - 2019

A STUDY TO EVALUATE HISTOPATHOLOGICAL VARIATIONS IN ENDOMTERIAL BIOPSIES IN A TERTIARY CARE HOSPITAL

Mrs A. R. Jaswanthini, Ms Ruchita D Jain

Abstract :

OBJECTIVE: 1. To evaluate endometrial variation in women with abnormal uterine bleeding. 2. To study spectrum of patterns of endometrium in different age group. MATERIALS AND METHODS: A retrospective study was undertaken to review the histopathological reports of all endometrial biopsies over a period of 3 months i.e March 2019 to May 2019 in Department of Pathology, Government Medical College, Omandurar Government Estate. Data was entered in Microsoft Excel. Analysis was done in the form of percentage and represented as tables where necessary. RESULT: A total of 100 patients were evaluated during the study period. Maximum number of cases were observed in age group of 35–45 years with secretory phase of endometrium (43%) being the most common functional lesion. Other endometrial patterns as in pie chart, were proliferative phase (31%), complex atypical hyperplasia of endometrium (2%), simple atypical hyperplasia of endometrium (4%), complex hyperplasia of endometrium without atypia (8%), simple hyperplasia of endometrium without atypia (12%) The incidence of various endometrial patterns in different age groups is as follows 15–25 years– 9%, 25–35 years– 23%, 35–45 years– 50%, 45–55 years–18%. CONCLUSION: In my study the most frequent endometrial pattern noted was secretory endometrium. The endometrial sampling using pipelle is preferred because it is safe, accurate and a cost effective outpatient procedure which avoids general anaesthesia and has a high sensitivity and specificity10. Using endometrial biopsy, abnormal cells can be detected so that the patient can be treated accordingly at an early stage.