Volume : IX, Issue : I, January - 2019

Acute Dermal Toxicity and Wound Healing Activity of Mikania Micrantha Ointment in Rats

Dr. Dip Sundar Sahu, Dr. S. N. Upadhyaya, Dr. M. Bora, Dr. Larin Puia, Dr. Swapnil Chowdhary, Dr. M. M. Rao

Abstract :

Background: The plant, Mikania micranntha Kunth. has been traditionally used as a wound healing drug since ancient times, but its scientific evaluation is not fully explored yet. The objective of our study was to evaluate acute dermal toxicity and wound healing activity of a M. micrantha ointment in rats. Methods: Excision wound model was used in current study. The effect of test drug was assessed from wound contraction. Results and Conclusions: The M. micrantha ointment showed moderate rate of contraction of wound that was slightly less than that of the standard drug, mupirocin. The M. micrantha ointment was also non–toxic to rat skin, suggesting a good potential of developing an inexpensive M. micrantha ointment for promoting accelerated wound healing.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

ACUTE DERMAL TOXICITY AND WOUND HEALING ACTIVITY OF MIKANIA MICRANTHA OINTMENT IN RATS, Dr.Dip Sundar Sahu, Dr. S.N.Upadhyaya, Dr.M.Bora, Dr.Larin Puia, Dr. Swapnil Chowdhary, Dr. M.M.Rao INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-1 | January-2019

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