Acute Viral Upper Respiratory Tract Infections in Pediatric Oncology Patients Undergoing Chemotherapy

Ayesha Hakim; Dr. Gaurav Salunke

Volume : IX, Issue : IX, September - 2019

Acute Viral Upper Respiratory Tract Infections in Pediatric Oncology Patients Undergoing Chemotherapy

Ayesha Hakim, Dr. Gaurav Salunke

Abstract :

Introduction: The mortality and morbidity in paediatric cancer patients has improved significantly over the last few years. However, viral infections continue to challenge the outcome in these children. Methodology: A retrospective analysis to determine the etiology of acute upper respiratory tract viral infection in 40 paediatric patients undergoing chemotherapy was conducted. Nasopharyngeal swabs (NPS) were collected in these patients and analysed using Biofire Respiratory kit RP2 plus. Results: A total of 38 viruses were detected from 40 NPS. In 6 patient samples, more than one virus was detected. Human Rhinovirus/ Enterovirus (n=17) was the most commonly detected isolate in this study. Age group of 1– 6 years (n= 26 viruses) was most commonly affected and prevalence of viral infection was found to be more common among the males (n= 24) Conclusion: Rapid detection of a viral pathogen may provide the physician with an upper hand in initiating appropriate treatment, thereby reducing the financial burden imposed on the health system, and providing direct improvement in morbidity and mortality of children with cancer.