Adult onset Fulminant form of Subacute Sclerosing  Panencephalitis :a case report

Dr. K.B.R. SASTRY; Dr. SUNIL KUMAR; Dr. P. ANURADHA; Dr. P. PRIYADARSHINI; Dr. M.A. MUJEEB AFZAL

Volume : V, Issue : X, October - 2015

Adult onset Fulminant form of Subacute Sclerosing Panencephalitis :a case report

Dr. K. B. R. Sastry, Dr. Sunil Kumar, Dr. P. Anuradha, Dr. P. Priyadarshini, Dr. M. A. Mujeeb Afzal

Abstract :

Subacute sclerosing panencephalitis (SSPE) is a progressive fatal neurological disorder caused by a persistent measles virus infection. It usually occurs in childhood and adolescence and may not be readily recognized when presenting later in life. The incidence of adult onset SSPE is reported to be between 1–1.75% and 2.6%1,2 . we report a case of 19 year old female patient with complaints of altered behaviour for 30 days and myoclonic jerks for 5 days. She had a past history of measles at the age of 5 years. Her MRI ain showed hyperintensities in bilateral parietooccipital lobes and frontal lobe in subcortical location. Electroencephalogram showed rademecker complexes. Measles IgG antibodies were detected in CSF and serum. She was diagnosed with SSPE stage II. She deteriorated rapidly and succumbed to death in 40 days. This was an atypical presentation of SSPE with regards to age, rapid progression and normal fundus