Age-Based Interpretation of Anti-Mullerian Hormone (AMH) Levels in fertile and infertile Women

Sahana K.R; Pranathi M; Geetha H; Ravikumar H.N

Volume : X, Issue : III, March - 2020

Age-Based Interpretation of Anti-Mullerian Hormone (AMH) Levels in fertile and infertile Women

Sahana K. R, Pranathi M, Geetha H, Ravikumar H. N

Abstract :

INTRODUCTION: Data related to AMH levels in fertile women are scarce, making interpretation for this population difficult. We aimed to characterize age–based AMH levels both in fertile and infertile women population to simplify interpretation of AMH results. This study represents the largest analysis to date of AMH levels in fertile women. Materials and Methods: This cross–sectional study analyzed serum AMH from 543 infertile women and 492 healthy controls, whose mean ages were 20–50 years. Sample collection was performed by random sampling and analyzed with SPSS version 16 software. AMH levels were abstracted from electronic medical records. AMH levels were measure by an independent laboratory RV Metro Polis by Chemiluminescence method. Results: There were significantly lower mean serum AMH levels among infertile women compared to the control group. The mean AMH serum levels from different ages of infertile and control group (fertile women) decreased with increasing age. Conclusion: We have observed decreased AMH levels with increasing age both in fertile and infertile women from 20 to 50 years of age. Assessments of AMH levels indifferent age group of female can help in predicting ovarian reserve in infertile women