Aminotransferases and Total Serum Bilirubin Level Derangement in Patients with Dengue Infection

Gupta R; Tomar R; Kumar M; Verma S; Dubey M

Volume : X, Issue : II, February - 2020

Aminotransferases and Total Serum Bilirubin Level Derangement in Patients with Dengue Infection

Gupta R, Tomar R, Kumar M, Verma S, Dubey M

Abstract :

Background: Dengue infection can affect the liver with a wide spectrum of manifestations. The aim of this study was to evaluate the impact of dengue virus infection on liver function by measuring aspartate aminotransferase (AST), alanine aminotransferase (ALT) and total serum bilirubin levels in patients serologically diagnosed with NS1 ELISA. Methods: NS1 ELISA positive patients were included in the study and all the patients underwent aminotransferase and bilirubin analysed. Results: AST was elevated more as compared to ALT and hyperbilirubinemia was observed in 9.2% of cases. Conclusion: Transaminase level analysis in dengue patients are crucial markers for severe acute liver cell injury.