An evaluation of newly developed C–reactive  protein slide Latex agglutination test against  Immunoturbidimetric test for diagnosis of neonatal  septicaemia

Pranav R. Naik; Dr. Pratibha B. Desai

Volume : III, Issue : VII, July - 2013

An evaluation of newly developed C–reactive protein slide Latex agglutination test against Immunoturbidimetric test for diagnosis of neonatal septicaemia

Pranav R. Naik, Dr. Pratibha B. Desai

Abstract :

CRP, the classic acute–phase protein of human serum is synthesized by Hepatocyte. Normally it is present only in trace amount in serum but it can increase by as much as 1000 fold in response to injury or infection. It falls quickly after efficient elimination of microbial stimulus, due to its short half life of 19 hours. Serial CRP measurement is a good practical guide for discontinuing antibiotic therapy in neonates with suspected sepsis. In present study we have compared newly developed quantitative slide agglutination test with quantitative test for measurement of CRP in sample from suspected cases of Neonatal sepsis. We have observed very high correlation between two methods in normal as well as abnormal samples.