An observational study of clinical pattern of adverse cutaneous drug reactions and causative agents in tertiary health care center.

Dr. Vimmi Agrawal; Dr. S. P. Pandey; Dr. Usha Gupta

Volume : V, Issue : VII, July - 2015

An observational study of clinical pattern of adverse cutaneous drug reactions and causative agents in tertiary health care center.

Dr. Vimmi Agrawal, Dr. S. P. Pandey, Dr. Usha Gupta

Abstract :

Adverse cutaneous drug reactions (ACDRs) are caused by a wide variety of agents. The pattern of cutaneous ADR and the drugs responsible for them is changing every year. Aims: Our objective was to evaluate the clinical pattern of ACDRs and the causative drugs in the tertiary health care center. Methods: fifty five patients with adverse cutaneous drug reactions were recruited for this study during 2013–2014. Results: The Most of ACDRs belonged to the age group of 21–30 years (27.27%). The male to female ratio was1.75:1. The most common eruptions observed were maculopapular rash (41.81%) followed by fixed drug eruption (20%), Erythema multiforme and SJS/TEN (10.90%), and the most common causes were NSAIDs followed by antimicrobial agents. Conclusion: The pattern of ACDRs And the drugs causing them is remarkably different in our population. Knowledge of these drug eruptions, the causative drugs and the prognostic indicators is essential for the clinician.