Volume : V, Issue : VI, June - 2015

ANALYSIS OF SUICIDAL ATTEMPTS INSCHIZOPHRENICS" N ASRAM HOSPITAL, ELURU

Dr. Dr. Syed Ahammad Basha. G, Dr. R. Somasundara Babu

Abstract :

 BACKGROUND AND OBJECTIVES Schizophrenia is a complex neurobehavioral disorder that appears to be closely associated with suicidal behavior. Suicide is a major cause of premature death among patients suffering from schizophrenia.The present study is carried to study the frequency of suicide attempts in persons with schizophrenia and to compare various clinical and socio demographic variables of patients suffering from schizophrenia with and without suicide attempts, in search of possible risk factors for suicide in schizophrenia. METHODOLOGY 100 consecutive patients suffering from schizophrenia based on ICD–10 diagnostic criteria,fulfilling inclusion and exclusion criteria, attending the outpatient department were studied using Semi–structured proforma, SAPS, SANS,CDSS,Beck’s Suicide intent scale and clinical interview.The study is a cross sectional descriptive study.Statistical analysis was done using the chi–square test and the unpaired t–test. RESULTS Out of 100 patients studied, 27% had attempted suicide(n=27). Individuals who had a family history of suicide,prominent positive symptoms and depressive features,who were in their early stages of illness(first few years), had more suicidal attempts compared to those who did not have. We did not find any significant association between the various demographic variables,subtype of illness,negative symptoms,duration of illness, and the suicidal behavior. CONCLUSIONS People suffering from schizophrenia are at a highrisk for making suicidal attempts, especially when the illness is acute and severe, in early stages, when accompanied by depressive symptoms. Early identification of risk factors and employment of possible preventive strategies,and effective monitoring of treatment would definitely make us keep a step towards meeting one of the greatest unmet challenges in psychiatry, “Suicide inSchizophrenia.” LIST OF ABBREVIATIONS CDSS – Calgary Depression rating scale for schizophrenia D–FEN – D fenfluramine DST – Dexamethasone suppression test EEG – ElectroEncephaloGraphy EPS – Extrapyramidal symptoms 5–HTR – Serotonin receptor 5–HTTgene – Serotonin transporter gene IL–6 – Interleukin 6 MAO A – Monoamineoxidase A PRL – Prolactin REM – Rapid Eye Movement sleep SANS – Scale for assessment of negative symptoms SAPS – Scale for assessment of positive symptoms SNP – Single nucleotide polymorphism TPH 1 – Tryptophan hydroxylase1 gene

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Dr. SYED AHAMMAD BASHA.G, Dr. R. Somasundara Babu Analysis of Suicidal Attempts Inschizophrenics�N Asram Hospital, Eluru Indian Journal of Applied Research, Vol.5, Issue : 6 June 2015

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