Volume : IV, Issue : III, March - 2014

Analysis of Variable Dose i –131 Treatment in Management of Hyperthyroidism

Dr Sujit Suresh Nilegaonkar, Dr Gouri Gulavani

Abstract :

Radioiodine therapy is an established mode of treatment for thyrotoxicosis of large range of etiologies. Different therapeutic regimes have been attempted to institute appropriate dose of radio iodine in different clinical scenario. However the indications, patient selection criteria and dose regime choice remain highly controversial varying greatly from institution to institution. The objective of this study is to assess the efficacy of three different ranges of variable doses of 131 radio Iodine therapy in patients with hyperthyroidism and to evaluate the incidence of hypothyroidism following radio iodine therapy at different doses. In this retrospective study, 127 patients treated with I–131 for hyperthyroidism between Jan 2006 – Jan 2007 was included who had regular follow up till one year. The patients were categorized in three groups and treated with different dosage This study shows that there is no definitive evidence of prolonging hypothyroidism in patients treated with small dose as compared to other two groups but often necessitating requirement of second dose of I 131. Our study indicates that the optimal dose of 5mCi of radioiodine should be given for the complete cure of hyperthyroidism to minimize the necessity of multiple doses.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr Sujit Suresh Nilegaonkar, Dr Gouri Gulavani Analysis of Variable Dose i -131 Treatment in Management of Hyperthyroidism Indian Journal of Applied Research, Vol.IV, Issue. III

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