Volume : X, Issue : VI, June - 2020

Angelman Syndrome

Tushar Noel

Abstract :

Firstly, Harry Angelman was a pediatrician who reported this case. Angelman syndrome is a congenital disorder caused by the absence of a specific gene which is transmitted through mother’s chromosome 15 and causes late development, difficulty in speech and balance, intellectual disability, and sometimes, seizures, tremors of limbs, the small size of the head and a matchless behavior with a happy manner that includes recurrent laughing, smiling, and sensibility. The prevalence of Angelman syndrome is approximate to be out of 1,065,070,607 populations, children pretended by Angelman syndrome are 88,755. It shows less prevalence rate. At 12 months of age, the sign or symptoms may start to begin and the most common symptom is delayed development in children. At the age of 2 and 3 years old, Seizures may begin. Angelman syndrome is caused by the loss of the normal contribution to the area of chromosome 15 from the mother which is called the ubiquitin–protein ligase E3A (UBE3A) gene. It is equally severe for both males and females. At the time of treatment, health workers focus on leading medical, sleep, and developmental problems. There is no cure for Angelman syndrome but we can treat the child patient on the basis of signs and symptoms. The background of this disease is rare

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

ANGELMAN SYNDROME, Tushar Noel INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-6 | June-2020

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