ANTIBIOGRAM OF GRAM NEGATIVE BACTERIAL ISOLATES FROM INTENSIVE CARE UNIT AT A TERTIARY CARE HOSPITAL

Ms.Reena Rajan; Dr.A.Venkata Raghavendra Rao

Volume : VI, Issue : V, May - 2016

ANTIBIOGRAM OF GRAM NEGATIVE BACTERIAL ISOLATES FROM INTENSIVE CARE UNIT AT A TERTIARY CARE HOSPITAL

Ms. Reena Rajan, Dr. A. Venkata Raghavendra Rao

Abstract :

 Gram negative bacterial infections continue to be one of the leading causes of morbidity and mortality in ICUs. The knowledge of antibiotic resistance pattern of these isolates facilitates effective empirical therapy, thereby preventing the emergence and spread of resistant microorganisms. This study is done to determine the antibiotic resistance pattern of Gram negative bacilli (GNB) from ICUs. GNB obtained from various clinical specimens were identified by standard biochemical methods & Antibiotic sensitivity testing was performed. Out of 696 samples studied, GNB was isolated from 185 (26.58%). The predominant GNB isolated were Klebsiella spp, followed by Acinetobacter spp, E.coli, Pseudomonas spp and Proteus.spp. About 69.73% of GNB were resistant to the fluoroquinolone tested. Among the aminoglycosides, 57.84% were resistant to netilmicin, 61.08% to amikacin and 70.81% to gentamicin, and 67.00% to third generation cephalosporins. Acinetobacter spp was the most resistant isolate to the antimicrobials tested.