Antibiotic sensitivity pattern of clinical isolates of  Proteus species with special reference to ESBL and  Amp C production

Dr Suchitra Shenoy M; Mohit; Dr. Richa Sinha

Volume : III, Issue : III, March - 2013

Antibiotic sensitivity pattern of clinical isolates of Proteus species with special reference to ESBL and Amp C production

Dr Suchitra Shenoy M, Mohit, Dr. Richa Sinha

Abstract :

Proteus spp are gram negative bacilli which can cause both community acquired and nosocomial infections. This study was conducted to note the antibiotic sensitivity pattern, production of ESBL and AmpC by clinical isolates of Proteus spp in a tertiary care center. Antibiotic sensitivity testing was done according to CLSI guidelines. The proteus isolates were sensitive to third generation cephalosporins, carbepenems and piperacillin/tazobactam. 20% of the isolates were ESBL and 28.5% were AmpC positive. 50% of the isolates were resistant to fluoroquinolones. 21 proteus isolates exhibited multidrug resistance. This may be due to the transfer of multiple genes from one bacterial population to another. Recognition of resistance pattern of bacteria is necessary from time to time to give appropriate treatment and avoid adverse clinical outcomes.