ANTIHYPERLIPIDEMIC AND ANTIATHEROGENIC EFFECT OF KOMBUCHA IN STREPTOZOTOCIN INDUCED DIABETIC RATS

Flora Olinda Dias; Chandrakala Shenoy K

Volume : VI, Issue : IV, April - 2016

ANTIHYPERLIPIDEMIC AND ANTIATHEROGENIC EFFECT OF KOMBUCHA IN STREPTOZOTOCIN INDUCED DIABETIC RATS

Flora Olinda Dias, Chandrakala Shenoy K

Abstract :

Oxidative stress has a major role in the pathogenesis of diabetic complications. The purpose of the present study was to investigate the possible protective effect of traditional fermented beverage kombucha on lipid profile and liver functions in streptozotocin (STZ) induced diabetic rats. The effect of kombucha on fasting blood glucose, lipid profile, atherogenic index (AI), cardiovascular indices, and the hepatic enzyme markers was examined in all the groups. Oral administration of kombucha significantly reduced fasting blood glucose, lipid parameters, AI, atherogenic coefficient, cardiac risk ratio and increased the levels of high density lipoproteins in diabetic rats. Thus, it can be concluded that kombucha treatment significantly alleviated the altered glycemic and lipidemic distress and protects against the risk of developing atherosclerosis in STZ – induced diabetic rats.