Volume : VI, Issue : VII, July - 2016

Antimicrobial Susceptibility Pattern and Detection of Metallobetalactamase production in Acinetobacter Species Isolated from Clinical Samples.

Dr. Abhilasha Bansal, Dr. Rekha Bachhiwal, Dr. Rajni Sharma, Dr Anita Singhal, Dr. R. K. Maheshwari

Abstract :

<p> Background: Acinetobacter species are common nosocomial pathogens and are resistant to several antibiotics in clinical practice. Metallo–beta–lactamse (MBL) mediated resistance to carbepenems is an emerging threat among isolates of Acinetobacter species Objectives: To study the antimicrobial susceptibility pattern of Acinetobacter isolates and detection of MBL production by phenotypic methods Materials and Methods: 200 Acinetobacter isolates from various clinical samples were subjected to antimicrobial susceptibility testing. ..Imipenem resistant strains were further processed to detect MBL production. Results: Acinetobacter baumannii was the most common species isolated (75.5%) from blood and respiratory samples from ICU patients. Maximum susceptibility was seen with Polymyxin B (91%) and colistin( 87%). Among 106 Imipenem resistant isolates, 95 (89.62%) were found to be MBL producers using MBL E–test. Majority of MBL producing Acinetobacter were XDR (97.89%) followed by PDR (10.52%) and MDR. (2.1%). Conclusion: High prevalence of MBL producing Acinetobacter spp among imepenem resistant strains demonstrated in our study calls for regular monitor of carpapenem resistance to control infections due to these bacteria.</p>

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Abhilasha Bansal, Dr. Rekha Bachhiwal, Dr. Rajni Sharma, Dr Anita Singhal, Dr. R.K. Maheshwari Antimicrobial Susceptibility Pattern and Detection of Metallobetalactamase production in Acinetobacter Species Isolated from Clinical Samples. Indian Journal of Applied Research, Vol.6, Issue : 7 JULY 2016

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