Volume : V, Issue : XI, November - 2015

ASSESSMENT ENDOTHELIAL DYSFUNCTION IN ESSENTIAL HYPERTENSION DURATION OF 2 YEARS BY ULTRASONOGRAPHY.

Dr Pankaj Patil, Dr Sumit Shejol, Dr K P Pathak

Abstract :

 Essential hypertension is most common type among two type of hypertension. It is associated with inflammation and dysfunction of endothelial. Endothelial dysfunction Is decreased release of NO from endothelial and dilation of artery. It’s a early step in artherosclerosis and thrombogenesis in hypertensive patients. AIMS AND OBJECTIVES : compare Pulse Wave Velocity with Flow Mediated Dilation, considering Flow Mediated Dilation as the gold standard non–invasive method for assessment of endothelial dysfunction. MATERIAL AND METHODS: The retrospective study. Total 50 patients of essential hypertension of 2years duration were included .data was collected from radiology and medicine department. Flow mediated dilation was measured at achial artery after hyperemia and after glyceryl trinitrate sublingually. RESULT:40 patients had endothelial dysfunction. Maximum Patients with duration of 18 to 24 month had endothelial dysfunction(100%). the prevalence of endothelial dysfunction as determined by PWV analysis is also approximately 80%; this is almost similar to that detected by FLOW MEDIATED DILATION CONCULSION:Endothelial dysfunction and its severity is increased with duration of essential hypertension. Pluse wavw velocity and flow mediated dilation has similer sensitivity and specificity for diagnosis of dysfunction.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

DR PANKAJ PATIL, DR SUMIT SHEJOL, DR K P PATHAK / ASSESSMENT ENDOTHELIAL DYSFUNCTION IN ESSENTIAL HYPERTENSION DURATION OF 2 YEARS BY ULTRASONOGRAPHY. / Indian Journal of Applied Research, Vol.6, Issue : 11 November 2016

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