Assessment of ankle brachial index and autonomic reactivity among ABO blood groups in type 2 diabetic patients

Mr Vinubalan V; Dr Karthik S; Dr. Sadishkumar Kamalanathan; Dr Madhavan C

Volume : X, Issue : IV, April - 2020

Assessment of ankle brachial index and autonomic reactivity among ABO blood groups in type 2 diabetic patients

Mr Vinubalan V, Dr Karthik S, Dr. Sadishkumar Kamalanathan, Dr Madhavan C

Abstract :

Background: Diabetes mellitus is a potential risk factor for many cardiovascular complications. Similar to neuropathy, peripheral arterial disease (PAD) is one of the reasons for repeated foot ulcers, chronic infections and poor wound healing in diabetes. ABO blood group antigen expression is also considered as an independent risk factor for cardiovascular complications due to the association with the lipid metabolism and coagulation status. There is paucity of reports in assessing the cardiovascular risk by autonomic functions among the ABO blood groups in diabetes mellitus. Aim: To assess the ankle achial index and autonomic reactivity among ABO blood groups in type2 diabetes mellitus Methodology: In this cross–sectional study, 67 type2 diabetic mellites patients without any complication participated. Autonomic reactivity tests and ankle achial index were estimated and compared between non–O and O blood group participants. Mann–Whitney test and t–test were used to compare the mean between the groups based on the type of data distribution. Results & Conclusion: Though heart rate response in the postural challenge (lying to standing test) was within the normal range in both non–O and O blood groups, there was relatively lower vascular response in the isometric handgrip test observed in the non–O blood group. Reduction in the ankle achial index was also observed in the non–O blood group and it was statistically significant compared to O blood group, in the type 2 diabetic patients without any complications.