Assessment of Fibrinogen Level in Relation to Risk Factors in Stroke Types

Dr. THRILOK CHANDER BINGI; Dr. KONDAL REDDY.S; DR. MANJULA; DR. RAMULU.B

Volume : V, Issue : IV, April - 2015

Assessment of Fibrinogen Level in Relation to Risk Factors in Stroke Types

Dr. Thrilok Chander Bingi, Dr. Kondal Reddy. S, Dr. Manjula, Dr. Ramulu. B

Abstract :

 Background: Fiinogen is important in the development of premature atherosclerosis. Hence, fiinogen 

levels are to be measured in patients with stroke at the earliest and to be treated.

Aims and Objectives:

To study plasma fiinogen levels and establish the coexistence of raised fiinogen levels with other possible risk factors in stroke patients.

Study design: Cross sectional, case control observational study. 

Materials and methods:

 This study was conducted in 40 stroke patients confirmed by CT ain between May2013 and August 2014. 40 age 

and sex matched controls were studied with regards to fasting lipid profile and plasma fiinogen levels.

Statistical methods:

 Chi–square test, Analysis of variance (ANOVA) and other suitable statistical methods were used. P value of < 

0.05 is taken as significant.

Results: The Plasma Fiinogen levels were significantly increased in both ischemic 465.5+/–66.984mg/dl (range 

320â”€620 mg/dl) & hemorrhagic 409.65+/–67.9mg/dl (range 313–550 mg/dl) stroke groups of patients (more so in ischemic stroke patients) when compared to controls (300.75+1– 52.74mg/dl) (range 150–450 mg/dl P value <0.004 (statistically significant) 

Conclusion: Increased Fiinogen level acts as an independent risk factor in etiology of Stroke. Plasma Fiinogen 

helps in predicting future adverse events. 