Volume : IX, Issue : IV, April - 2019

ATTENUATION OF HEMODYNAMIC RESPONSE IN MODIFIED ECT USING DEXMEDETOMIDINE

Dr. B Shakeela Begum, Dr. D. Hemamalini

Abstract :

BACKGROUND: Electroconvulsive therapy is used to treat psychiatric disorders associated with initial parasympathetic response later by a sympathetic response like tachycardia and hypertension which can results in myocardial infarction and cardiac arrest in vulnerable people. The objective of our study to evaluate the efficacy of dexmedetomidine in attenuating the hemodynamic response to modified ECT and its effect on seizure duration, time of recovery and the agitation score. MATERIALS AND METHODS: This randomised prospective double blinded cross over study was carried out in 50 patients, divided into two groups (the same patient acts as both control and study in separate sittings). Group C received 100ml of plain normal saline intravenously over 10min,and Group D received dexmedetomidine 0.5μg/Kg in 100ml saline 10 minutes prior to induction. Anaesthesia was standardized in both groups and vital parameters, Motor seizure duration, the time taken for the recovery of the patient and agitation score were recorded at 1, 2, 5,10,20,30,60,minutes and 2,4 hours after the ECT shock. RESULTS: There was statistically significant fall in SBP, DBP, (MAP), heart rate in the dexmedetomidine group (p value=0.0006), (p value=0.004), (p value=0.013) and (p value –0.0001) respectively. The agitation score was lower in group D compared to group C which was statistically significant (p value=0.0001) but no significant difference in saturation (p value >0.05). CONCLUSION: Dexmedetomidine at a dose of 0.5μg/Kg given before Modified ECT attenuates the hyper dynamic response with a slight delay in time for recovery.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

ATTENUATION OF HEMODYNAMIC RESPONSE IN MODIFIED ECT USING DEXMEDETOMIDINE, DR.B SHAKEELA BEGUM, DR. D. HEMAMALINI INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-4 | April-2019


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