Attenuation of Pressor Response:a Comparison of  Diltiazem and Esmolol.

Dr. Adnanali Sarkar; Dr. Sameer Kulkarni; Dr. Shalini Thombre

Volume : III, Issue : VIII, August - 2013

Attenuation of Pressor Response:a Comparison of Diltiazem and Esmolol.

Dr. Adnanali Sarkar, Dr. Sameer Kulkarni, Dr. Shalini Thombre

Abstract :

Laryngoscopy during general anaesthesia results in stimulation of the larynx, pharynx, epipharynx and trachea leading to sympathetic system activation leading to various cardiovascular changes like increase in heart rate, blood pressure, intracranial tension, intraocular pressure, dysrrhythmias, cardiac asystole and even sudden death. The recent reports of effectiveness of various calcium channel blockers like diltiazem and Esmolol a beta–antagonist with short half–life and easy availability of both promoted us to study their efficacy in preventing pressor response to laryngoscopy and endotracheal intubation. The results showed that Diltiazem attenuates the haemodynamics pressor responses during laryngoscopy and intubation better than Esmolol although attenuation in both the groups is comparable