IJAR - Indian Journal of Applied Research

Dr. Tomsy Alukkal; Dr. Shakuntala Goswami; Dr. Angad Singh; Dr. Mona Vasudev Bilandani; Dr. Maria Joseph

Volume : IX, Issue : VII, July - 2019

ATTENUATION OF PRESSOR RESPONSE TO LARYNGOSCOPY AND INTUBATION: COMPARITIVE STUDY BETWEEN NITROGLYCERIN SPRAY AND LIDOCAINE SPRAY.

Dr. Tomsy Alukkal, Dr. Shakuntala Goswami, Dr. Angad Singh, Dr. Mona Vasudev Bilandani, Dr. Maria Joseph

Abstract :

AIM: Laryngoscopy and tracheal intubation provoke transient but marked sympathetic response. We conducted this study to compare the effect of NTG SPRAY AND LIDOCAINE SPRAY before laryngoscopy and endotracheal intubation, on hemodynamic responses in normotensive patient. MATERIALS AND METHODS: In a prospective randomized controlled trial, 100 adult patients of ASA I, II, 18–60 year posted for elective general surgery under general anesthesia with intubation were randomly allocated to two groups as Group A – receiving 1 NITROGLYCERIN spray (0.4mg/spray)and Group B – receiving LIDOCAINE spray(10mg/spray) one minute before intubation. SBP, DBP,MAP, heart rate were recorded at baseline, just before intubation ,immediately after intubation, and every minute for 10 mins. RESULTS: The rise in SBP was significantly higher in Lidocaine group from the time of Laryngoscopy till 4 mins ( p<0.05).There is significant attenuation in DBP caused by NTG spray in the immediate post intubation period (p<0.05) .There is significant increase in MAP in Lidocaine group in the immediate post intubation period (p<0.05). CONCLUSIONS:Lignocaine as compared to nitroglycerine is more effective in attenuating the HR and BP changes to laryngoscopy & intubation.