ATYPICAL VARICELLA ZOSTER INFECTION WITH SECONDARY HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS SYNDROME: A CASE REPORT

Dr. Angeline Sophia Rajakumar; Dr. Madhavan K.; Dr; Priyadarshini V.; Dr. Nandini Ravi

Volume : VII, Issue : IV, April - 2017

ATYPICAL VARICELLA ZOSTER INFECTION WITH SECONDARY HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS SYNDROME: A CASE REPORT

Dr. Angeline Sophia Rajakumar, Dr. Madhavan K. , Dr, Priyadarshini V. , Dr. Nandini Ravi

Abstract :

Chicken pox is caused by varicella zoster virus (VZV) which is a dermatotropic and neurotrophic virus that usually produces primary infection in childhood. The disease in children is usually well–tolerated. Manifestations are more severe in adults, pregnant women and immunocompromised. Clinical symptoms of VZV infection include fever with rashes progressing from small pink macules to vesicles and pustules in a centripetal distribution, with fresh crops every 2–4days. Atypical manifestations include pneumonitis, hepatitis, encephalitis and cerebellitis. The following case describes a patient with VZV infection presenting with fever, rashes, abdominal pain and history of giddiness and swaying on walking. Patient developed secondary haemophagocytic lymphohystiocytosis syndrome (HLH), which is a rare complication. after 4 days and was managed symptomatically. This case is atypical in terms of the rapidity of clinical deterioration and multi organ systems involvement along with secondary HLH.