Volume : III, Issue : V, May - 2013

Biofilm Forming Abilities and Antibiotic Susceptibility Pattern of Clinical Isolates of Staphylococcus aureus

Jayashri Apurva, Dipali Barate, M. Musaddiq

Abstract :

Microorganisms growing in a biofilm are associated with chronic and recurrent human infections and are highly resistant to antimicrobial agents. The objective of this study was to observe the biofilm forming abilities, which is an important virulence factor and to study antibiotic susceptibility pattern of clinical isolates of Staphylococcus aureus. Clinical specimens received from various hospitals and pathological laboratories of Akola city. Out of 38 isolates of S. aureus 20 (52.63%) isolates were found to be biofilm producers by Standard tube (ST) method and 11 (28.94%) were by Congo red agar (CRA) method. All the 38 isolates were checked for their antibiotic susceptibility by Kirby– Bauer method.It was found that multi drugs resistance (MDR) was shown by biofilm producers. The highest resistance was shown towards Penicillin, Ampicillin, Methicillin and Erythromycin while Vancomycin and Tetracycline were found to be the most effective agent against biofilm producing isolates. The susceptibility of isolates towards antibiotics was more amongst biofilm non producers. The cholic acid found to exert good antibacterial activity against drug resistant biofilm producers.  

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Jayashri Apurva, Dipali Barate, M. Musaddiq Biofilm Forming Abilities and Antibiotic Susceptibility Pattern of Clinical Isolates of Staphylococcus aureus Indian Journal of Applied Research, Vol.III, Issue.V May 2013


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