Biological evaluation of 1,4–disubstituted 1,2,3–triazole derivatives as plant pathogenic fungus inhibitors

Hana Ighachane; Hanane el ayadi; My Hassan Sedra; Hassan Bihi Lazrek

Volume : IV, Issue : VIII, August - 2014

Biological evaluation of 1,4–disubstituted 1,2,3–triazole derivatives as plant pathogenic fungus inhibitors

Hana Ighachane, Hanane El Ayadi, My Hassan Sedra, Hassan Bihi Lazrek

Abstract :

In order to create novel potent antifungal agents, the antifungal effects of 1,4–dissubstitued 1,2,3–triazole derivatives on plant pathogenic fungi were evaluated for bioactivity against two of the most  devastating fungal Verticillium dahliae Klep(Vd) and Fusarium oxysporum f.sp. albedinis (Foa) using the mycelia growth rate method and sporulation. Some of the compounds showed definite activities in vitro against the tested fungi at 20 μg/ml. For instance, Compound 2h can be used as a good starting point for further optimization. 