Volume : VII, Issue : X, October - 2017

Bone Marrow Aspiration; Role and Significance in Haematological disorders.

G. D. Katiyar, Anjana Arya, Parbodh Kumar

Abstract :

 Introduction: Bone marrow examination is regarded as one of the most important diagnostic procedures to assess various haematological disorders. The advantages of bone marrow aspiration are numerous. This study was conducted with the aim to evaluate the role of bone marrow aspiration and its significance in haematological disorders. Methods and Materials: This study was carried out in the Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly from January 2014 to December 2015. Total 144 patients came in our department for bone marrow examinations. Patients of all age groups and genders were included in the study. Those with inconclusive reports or inadequate samples were excluded from study. After taking history, clinical examination and complete blood counts, bone marrow was aspirated from posterior superior iliac spine under aseptic conditions. Smears were made, stained and examined under microscope. Results: Total 144 patients came in our department for bone marrow examinations. Out of which, 139 patients were included in this study. Among these, 86(61.8%) cases were diagnosed as anaemia, out of which 19(13.7%) cases of combined deficiency anaemia, 12(8.6%) cases of iron deficiency anaemia, 39(28.1%) cases of megaloblastic anaemia and 16(11.5%) cases of anaemia of chronic diseases. Total 17(12.2%) cases of leukemia, 12(8.6%) cases were of Chronic Myeloid Leukemia (CML), 4(2.9%) cases were of Acute Myeloid Leukemia (AML) and 1(0.7%) case of Acute Lymphoblastic Leukemia (ALL). Other cases included plasma cell dyscrasia 2(1.4%) cases, Immune Thrombocytopenic Purpura (ITP) 4 (2.9%) cases, hypoplastic/Aplastic marrow 13(9.4%) , normal reactive marrow 15(10.8%)  and 1(0.7%) case each of microfilaria and metastatic malignancy.

Out of 139 cases, 81(58.3%) were males and 58 (41.7%) were females. The male to female ratio was 1.3:1.According to cellularty of marrow, 15(10.8%) cases showed normocellular marrow, 111(79.9%) cases showed hypercellular marrow and 13 (9.4%) cases showed hypocellular marrow.

Conclusion: Bone marrow examination remains a simple, reliable and effective technique in the diagnosis of haematological conditions. The bone marrow examination is helpful in cases where routine investigations fail to reach a definite diagnosis.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

G.D. Katiyar, Anjana Arya, Parbodh kumar, Bone Marrow Aspiration; Role and Significance in Haematological disorders., INDIAN JOURNAL OF APPLIED RESEARCH : Volume-7 | Issue-10 | October-2017

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