Volume : V, Issue : VII, July - 2015

CA–125 MARKER STUDY WITH HISTOLOGICAL CORRELATION IN OVARIAN TUMOR

Dr. Bhavin B. Padhariya, Dr. Jitendra Chavda, Dr. V. C Popat

Abstract :

 Aim & Objective: To diagnose neoplasm with the use of CA–125 and to correlate it with stage of tumor. To use CA–125 as a prognostic marker. To study the changes in values of CA–125 after treatment and to study the effectiveness of the treatment. To use CA–125 values to study recurrence or metastasis after treatment. Materials & Methods: Total 100 patients who were admitted to various departments of G.G.Hospital, Jamnagar during the time period of January–2010 to July–2011 were selected. These patients were investigated for CA–125 level in their serum with the use of ELISA both pre operative and post operatively. Ca–125 value was correlated with histopathological diagnosis of suspected mass. Results: The specificity, overall sensitivity, sensitivity in malignant conditions, positive predictive value, negative predictive value are 83.33%, 63.79%, 83.33%, 84.09%, 62.5% respectively. Conclusion: As CA–125 test has low sensitivity and low specificity it cannot be used as a sole diagnostic measure and other supportive investigations are also required in many cases for diagnosis.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr.Bhavin B. Padhariya, Dr.Jitendra Chavda, Dr. V.C Popat Ca-125 Marker Study with Histological Correlation in Ovarian Tumor Indian Journal of Applied Research, Vol.5, Issue : 7 July 2015

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