Catheter-associated urinary tract infections caused by quinolone-resistant bacteria isolated from Assiut University Hospitals

Osama F. E. Hassanein; Khaled M. Hassanein; Ahmed S. Ahmed; Wafaa E. Soliman; Gamal F. M. Gad

Volume : VIII, Issue : XI, November - 2018

Catheter-associated urinary tract infections caused by quinolone-resistant bacteria isolated from Assiut University Hospitals

Osama F. E. Hassanein, Khaled M. Hassanein, Ahmed S. Ahmed, Wafaa E. Soliman, Gamal F. M. Gad

Abstract :

The aim of the study was investigation of ciprofloxacin–resistant bacterial isolates in cases with catheter–associated urinary tract infections (CAUTIs). Study objectives included isolation and identification of the bacterial isolates and determination of their antibiogram. For ciprofloxacin–resistant strains, the minimal inhibitory concentration was determined; host characteristics were also studied. The causative bacterial uropathogens detected in all the studied cases were headed by Klebsiella spp. (44.8%) followed by Pseudomonas aeruginosa (18.4%), Escherichia coli (17.6%) and Enterococcus species (14.4%). Quinolone resistance was found in 30 out of 100 patients studied (30%) and in 39 out of 125 bacterial isolates (31.2%). The highest rates of quinolone resistance were shown by Pseudomonas and Klebsiella spp. then E. coli. (39.1%, 32.1% and 31.8% respectively). It is noted that quinolone resistance was higher in patients with mixed bacterial infections (55.6%) than in patients with mono–bacterial infection (19.2%), that may suggest that mixed bacterial infection is a risk factors for development of quinolone resistance