Volume : X, Issue : VI, June - 2020

Changes of Vitamin D levels in Parkinson's disease in Libya

Dr. Hatem Fawzi Gharour, Dr. M. L. Rajeswari, Dr. Andrew J Bennett, Dr. Deborah J Briggs, Dr. Salima M Hawda, Dr. Abdelhamid El Zawawi, Dr. Peela Jagannadha Rao

Abstract :

Background: Parkinson’s is one of the major debilitating disorders in elderly people all over the world including Libya especially farmers. The biochemical studies shown that, serum vitamin D concentration was lower among Parkinson’s disease cases and it was also associated with age, sex, marital status, education, leisure–time physical activity, smoking, alcohol consumption, body mass index, diabetes, hypertension, and the serum cholesterol. The present study is to see how vitamin D levels in the serum of patients with Parkinson’s disease are related to its risk. Material and methods: A total 104 subjects, including control, were enrolled in the study and further grouped as, 52 clinically examined Idiopathic Parkinson’s disease patients (35 males and 17 females) while remaining 52 were taken as age and sex matched healthy controls. Serum vitamin D (25(OH)D) was determined from frozen samples, stored at baseline. Estimates of the relationship between serum vitamin D concentration and Parkinson’s disease incidence were calculated using Cox’s model. Results: The relative risk of the disease between the highest and lowest quartiles of vitamin D concentration was 0.35 (95% CI 0.15–0.81, p for trend=0.006). Conclusion:The results are consistent with the suggestion that high vitamin D status protects against Parkinson’s disease.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

CHANGES OF VITAMIN D LEVELS IN PARKINSON'S DISEASE IN LIBYA, Dr. Hatem Fawzi Gharour, Dr. M.L.Rajeswari, Dr. Andrew J Bennett, Dr. Deborah J Briggs, Dr. Salima M Hawda, Dr. Abdelhamid El-Zawawi, Dr. Peela Jagannadha Rao INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-6 | June-2020

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