Characterisation  of  Burkholderia  cepacia complex  isolates from clinical samples

Dr. T..S..Shailaja; Dr. A. Mohankumar

Volume : VI, Issue : IV, April - 2016

Characterisation of Burkholderia cepacia complex isolates from clinical samples

Dr. T. . S. . Shailaja, Dr. A. Mohankumar

Abstract :

Burkholderia cepacia complex (BCC), is an emerging pathogen which is capable of causing bacteremia and other invasive infections, predominantly in patients with cystic fiosis and also in non cystic fiosis patients. The objectives of the present study were to isolate, speciate and to find out the antibiogram of BCC from clinical samples. A total of 8929 samples were processed during seven months in a tertiary care centre in central Kerala. All the isolates morphologically resembling BCC were subjected to phenotypic characterization including antibiotic susceptibility testing by conventional and automated methods. We could obtain BCC isolates from 49 patients. Based on the biochemical reactions performed on 22 BCC isolates, 20 identified as Burkholderia cepacia, one as B. cenocepacia and the remaining one as B. stabilis genomic species [1,2] 97.96% of the isolates were sensitive to ceftazidime, 91.84% to co–trimoxazole, 71.43% to meropenem and all were resistant to colistin.