Volume : VI, Issue : VI, June - 2016
Chelation Status & clinical Profile of Thalassemic Children attending Paediatric clinics
Shyam Choudhari, M K Behera
Abstract :
BACKGROUND: Thalassemia is one of the most common hereditary disorders and beta thalassemia major is its severe form. The present study is concerned with the analysis of clinical profile, analysis of liver function and estimation of serum ferritin levels. Aim and Objectives: To study clinical profile of thalassemic children, and study serum ferritin levels. Materials & Method: All registered thalassemic children were included in this study, attending thalassemia clinics in Smt Kashibai Navale Medical College, Pune. Their height, weight, Clinical examination done and size of liver, spleen, hematological , biochemical , LFT and serum ferritin levels estimated. Result: Thirty children included in study, of which,14 girls(46.6%)and 16 boys(53.3%). Age ranged from 8 months to 9 years with the average age being 3.7 years. Typical haemolytic facies were seen in 16 children (53%). Sixteen children (53.3%) were found to be stunted. Haemoglobin levels ranged from 5 gm%to 9 gm% with average haemoglobin concentration 8 gm%. Consanguineous marriage detected in 8 parents(26.6%).Total number of blood transfusions ranged from 4 to 65 units with average number being 28. Liver was enlarged in all cases except two ranging from 2 cm to 12 cm with average of 4.43cm. Spleen was enlarged in all cases except 6, ranging from 1 cm to 10 cm with average being 3.6cm. SGOT levels were raised in 16 cases (53.3%). SGPT levels raised in 14 cases (46.6%).Serum ferritin levels were raised in all children with average of 3879.5 ng/ml. Conclusion: Serum ferritin levels were found to be high in all children and they require iron chelation therapy. So in all thalassemia patients serum ferritin levels to be monitored regularly
Keywords :
Article:
Download PDF
DOI : 10.36106/ijar
Cite This Article:
Shyam Choudhari, M K Behera Chelation Status & clinical Profile of Thalassemic Children attending Paediatric clinics Indian Journal of Applied Research, Vol.6, Issue : 6 JUNE 2016
Number of Downloads : 402
References :
<p>&lt;p&gt;&amp;lt;pre&amp;gt;&amp;lt;/pre&amp;gt;&lt;/p&gt;</p>
Shyam Choudhari, M K Behera Chelation Status & clinical Profile of Thalassemic Children attending Paediatric clinics Indian Journal of Applied Research, Vol.6, Issue : 6 JUNE 2016
<p>&lt;p&gt;&amp;lt;pre&amp;gt;&amp;lt;/pre&amp;gt;&lt;/p&gt;</p>
Our Other Journals...
-
International Journal of
Scientific Research Visit Website -
PARIPEX Indian Journal
of Research Visit Website -
Global Journal for
Research Analysis Visit Website