Volume : IX, Issue : VIII, August - 2019

Chromosomal Abnormalities Detected in Infertile Males – A Retrospective Study

Dr. Ashalatha Pr, Mrs. Manju. M

Abstract :

The present study was carried out to find out the frequency and types of chromosomal abnormalities in males attending the Infertility Clinic of Govt. Medical College, Kozhikode, which is a Tertiary Care Centre of North Kerala. Study settings and design: A retrospective study of karyotypes of 319 infertile males was done. The results of cytogenetic analysis of male patients over a period of 5 years (2014 January to 2018 December) were studied. Methods: Peripheral blood lymphocyte culture was done according to standard protocol and chromosomal analysis was carried out using Cytovision software version 7. Results: The results of present study show that the incidence of chromosomal abnormalities in infertile men is 18.45% which includes structural and numerical anomalies. The remaining 81.55% males showed apparently normal karyotypes. Conclusion: The results of this study indicate that in all phenotypic males with infertility, karyotyping should be done after excluding non–genetic causes. This will help in the precise diagnosis, management, possibility of ICSI, pre implantation diagnosis and genetic counseling for the couple.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

CHROMOSOMAL ABNORMALITIES DETECTED IN INFERTILE MALES‾A RETROSPECTIVE STUDY, Dr.Ashalatha PR, Mrs. Manju.M INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-8 | August-2019

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