Clinical and electrophysiological study of Gullian Barre Syndrome with reference to prognosis

Dr.P. RAJASEKHAR; Dr. C. SREENIVASULU; Dr. BHARATH BHUSHAN REDDY; Dr. PRATHAP BINGI

Volume : VI, Issue : II, February - 2016

Clinical and electrophysiological study of Gullian Barre Syndrome with reference to prognosis

Dr. P. Rajasekhar, Dr. C. Sreenivasulu, Dr. Bharath Bhushan Reddy, Dr. Prathap Bingi

Abstract :

Guillain Barre Syndrome(GBS) or Acute Polyradiculoneuritis is an acute, diffuse post–infective– disorder of the nervous system involving the spinal roots, the peripheral nerves and cranial nerves.The etiology is thought to be widespread demyelination of the spinal roots and the peripheral nerves due to a cross reaction between myelin and unconfirmed agents like viruses. Although GBS often has a benign prognosis, 7% of patients die and further 16% suffer residual disability.The modalities of treatment of GBS are physiotherapy supportive treatment ventilator management, plasma exchange and of late intravenous immunoglobulins. Early diagnosis of GBS favours a good outcome after treatment, this study was carried out to analyse the electrophysiological abnormalities. Electrophysiological studies play an important role in the early detection, characterization and treatment of GBS. This study was undertaken to study the clinical profile of GBS in Government General Hospital and to attempt to correlate certain clinical and electrophysiological features with prognosis.